Article
Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes.
Diabetes care - 1 Feb 2019
Triolo Taylor M, Fouts Alexandra, Pyle Laura, Yu Liping, Gottlieb Peter A, Steck Andrea K
Abstract excerpt
OBJECTIVE: There are variable reports of risk of concordance for progression to islet autoantibodies and type 1 diabetes in identical twins after one twin is diagnosed. We examined development of positive autoantibodies and type 1 diabetes and the effects of genetic factors and common environment on autoantibody positivity in identical twins, nonidentical twins, and full siblings. RESEARCH DESIGN AND METHODS:...
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