Article
Labeling of Collagen Type I Templates with a Naturally Derived Contrast Agent for Noninvasive MR Imaging in Soft Tissue Engineering.
Advanced healthcare materials - 1 Sept 2018
Janke Heinz P, Güvener Nihan, Dou Weiqiang, Tiemessen Dorien M, YantiSetiasti Anglita, Cremers Jozef G O, Borm Paul J A, Feitz Wout F J, Heerschap Arend, Kiessling Fabian, Oosterwijk Egbert
Abstract excerpt
In vivo monitoring of tissue-engineered constructs is important to assess their integrity, remodeling, and degradation. However, this is challenging when the contrast with neighboring tissues is low, necessitating labeling with contrast agents (CAs), but current CAs have limitations (i.e., toxicity, negative contrast, label instability, and/or inappropriate size). Therefore, a naturally derived hemin-L-lysine...
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