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Article

Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype.

Stem cell research & therapy - 16 May 2022

Andersen Camilla, Uvebrant Kristina, Mori Yuki, Aarsvold Stacie, Jacobsen Stine, Berg Lise Charlotte, Lundgren-Åkerlund Evy, Lindegaard Casper

Abstract excerpt

BACKGROUND: Mesenchymal stem cells (MSCs) have shown promising results in stimulating cartilage repair and in the treatment of osteoarthritis (OA). However, the fate of the MSCs after intra-articular injection and their role in cartilage regeneration is not clear. To address these questions, this study investigated (1) homing of labeled human adipose tissue derived integrin α10β1-selected MSCs (integrin α10-MSCs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35578319
DOI: 10.1186/s13287-022-02884-2
PMCID: PMC9109317

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