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Article

Exploratory Study on Genetic Variants Related to Hydatidosis Susceptibility and Albendazole Pharmacogenetics in the Cusco Region in Peru.

Frontiers in bioscience (Scholar edition) - 22 Sept 2025

Jaramillo-Valverde Luis, Garcia-Paitan Marlon Yuri, Landeo Dolly, Santivañez Saul J, Cacacabelos Ramon

Abstract excerpt

BACKGROUND: Hydatidosis, caused by Echinococcus granulosus, is a neglected zoonotic disease with significant public health implications in endemic regions, such as in Cusco, Peru. Genetic factors influencing susceptibility to infection and responses to albendazole, the primary treatment, remain unclear. Thus, this study aimed to investigates genetic polymorphisms associated with hydatidosis susceptibility and...

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Source

Identifiers

PMID: 41074479
DOI: 10.31083/FBS40566

Genes

CYP2B6
IL17A
TGFB1
VDR
CYP2E1
CYP3A4
FOXP3
IFNG
IL10
SLCO1B1
ABCB1
CTLA4
CYP1A2
IL12B
IL4
MBL2
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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