Article
Identification of Two Novel Mutations in KDM3A Regulatory Gene in Iranian Infertile Males
Iranian biomedical journal - 1 May 2019
Hojati Zohreh, Soleimanpour Elaheh, Javadirad Seyed-Morteza, Nasr-Esfahani Mohammad Hossein
Abstract excerpt
Background: KDM3A is a key epigenetic regulator expressed in the testis and is required for packaging and condensation of sperm chromatin. To this point, the association of the KDM3A gene with infertility has not been studied in human. The aim of this study was to screen any new mutation in KDM3A gene to explore more details of human male infertility. Methods: In this work, 150 infertile men (oligozoospermia and...
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