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Article

Novel biomarker ZCCHC13 revealed by integrating DNA methylation and mRNA expression data in non-obstructive azoospermia

26 Feb 2018

Abstract excerpt

Abstract The objective of this study was to identify genes regulated by methylation that were involved in spermatogenesis failure in non-obstructive azoospermia (NOA). Testis biopsies of patients with NOA and OA (with normal spermatogenesis) were evaluated by microarray analysis to examine DNA methylation and mRNA expression using our established integrative approach. Of the coordinately hypermethylated and...

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Share to Epigenetics and DNA Methylation
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 29531833
DOI: 10.1038/s41420-018-0033-x

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