Article
Identification of the PRM1 gene mutations in oligoasthenoteratozoospermic men.
Andrologia - 1 Dec 2020
Nasirshalal Mahzad, Tahmasebi-Birgani Maryam, Dadfar Mohammadreza, Nikbakht Roshan, Saberi Alihossein, Ghandil Pegah
Abstract excerpt
Mutations or altered expression of PRM1 gene have been associated with male infertility. This study aimed to analyse pathogenic variations of PRM1 gene in Iranian Arab infertile men with oligoasthenoteratozoospermia that was carried out for the first time in this population. Genomic DNA was used to perform PCR sequencing in PRM1 untranslated regions, exons and intron. Also, bioinformatics analysis was recruited...
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