Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex

27 Jul 2018

Abstract excerpt

PURPOSE: Human females have a unique duration of post-reproductive longevity, during which sex-specific mechanisms ma influence later-life mechanisms of neuronal resilience and vulnerability. The maintenance of energy metabolism, through the oxidative phosphorylation (OXPHOS) apparatus, is essential for brain health. Given the known association between reproductive period (years from menarche to menopause) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Menopause: Health Impacts and Treatments
Share to Neuroendocrine regulation and behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30052629
DOI: 10.1371/journal.pone.0199073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortexPMID 30052629Read ↗

Postmortem tissue biomarkers of menopausal transitionSemantic proximity Read ↗

Women’s brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer’s diseaseSemantic proximity Read ↗

Associations of endogenous and exogenous hormonal exposures and cardiovascular disease in women – A FinnGen studySemantic proximity Read ↗

Reproductive lifespan and hormonal therapy in relation to later-life neurovascular health: A population-based study of women in the Gothenburg H70-1944 Birth CohortSemantic proximity Read ↗

Human reproduction comes at the expense of faster aging and a shorter lifeSemantic proximity Read ↗

Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease.Semantic proximity Read ↗

Female-specific factors are associated with cognition in the UK Biobank cohortSemantic proximity Read ↗

Sex-specific hormone-sensitive regulatory architecture in adolescence as a scaffold for depression vulnerabilitySemantic proximity Read ↗

Parity is associated with cognitive function and brain age in both females and malesSemantic proximity Read ↗

Shared Genetics Between Age at Menopause, Early Menopause, POI and Other TraitsSemantic proximity Read ↗

Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.Semantic proximity Read ↗

The evolution of premature reproductive senescence and menopause in human femalesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.