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Novel Insights into Adult and Cancer Stem Cell Biology

27 Jul 2018

Abstract excerpt

Adult tissues are thought to harbor two populations of "dormant" and "actively dividing" stem cells. Quiescent stem cells undergo rare asymmetric cell divisions (ACDs) through which they self-renew and give rise to tissue-committed "progenitors" of distinct fate and "progenitors" in turn undergo symmetric cell divisions (SCDs) and clonal expansion. However, quiescent stem cells have not been demonstrated in adult...

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PMID: 30051749
DOI: 10.1089/scd.2018.0118

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