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Endogenous, very small embryonic-like stem cells: critical review, therapeutic potential and a look ahead

10 Sept 2016

Abstract excerpt

BACKGROUND: Both pluripotent very small embryonic-like stem cells (VSELs) and induced pluripotent stem (iPS) cells were reported in 2006. In 2012, a Nobel Prize was awarded for iPS technology whereas even today the very existence of VSELs is not well accepted. The underlying reason is that VSELs exist in low numbers, remain dormant under homeostatic conditions, are very small in size and do not pellet down at...

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PMID: 27614362
DOI: 10.1093/humupd/dmw030

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