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HLA DRB1*01:02 allele is associated with anti-AT1R antibodies production in kidney transplanted patients.

Human immunology - 1 Jun 2026

Carelli Ilaria, Romano Alessandro, Faini Angelo Corso, Caorsi Cristiana, Togliatto Gabriele Maria, Rosso Claudia Maria, Mazzola Gina, Garino Elena, Alizzi Silvia, Magistroni Paola, Biancone Luigi, Cantaluppi Vincenzo, Vaisitti Tiziana, Deaglio Silvia, Amoroso Antonio

Abstract excerpt

BACKGROUND: Kidney transplantation is lifesaving treatment for end-stage renal disease, yet immune-mediated complications limit long-term graft survival. Non-HLA antibodies (NHLA), particularly anti-Angiotensin type 1 receptor antibodies (AT1R-abs), are emerging mediators of graft injury. This study investigated whether selective HLA alleles influence AT1R-ab development in kidney transplant recipients. MATERIAL...

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Identifiers

PMID: 42062116
DOI: 10.1016/j.humimm.2026.111745

Genes

DR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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