Article
Early identification of renal transplant recipients with high risk of polyomavirus-associated nephropathy.
Medical microbiology and immunology - 1 Dec 2015
Teutsch K, Schweitzer F, Knops E, Kaiser R, Pfister H, Verheyen J, Göbel H, Cingöz T, Di Cristanziano V
Abstract excerpt
Polyomavirus BK (BKPyV) is ubiquitous among humans. Following primary infection, the virus remains latent predominantly in the hosts' uroepithelial cells. Up to 10 % of renal transplant recipients show a viral reactivation that can lead to polyomavirus-associated nephropathy (PyVAN). In the absence of early treatments, the risk of graft loss is up to 80 %. Monitoring viral load in urine and plasma by real-time...
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