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Article

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

Spine - 15 Feb 2019

Sheng Fei, Xia Chao, Xu Leilei, Qin Xiaodong, Tang Nelson Leung-Sang, Qiu Yong, Cheng Jack Chun-Yiu, Zhu Zezhang

Abstract excerpt

STUDY DESIGN: A genetic association study. OBJECTIVE: To determine whether common variants of fibrillin-1 (FBN1) and fibrillin-2 (FBN2) are associated with adolescent idiopathic scoliosis (AIS), and to further investigate to further investigate the functional role of FBN1 in the onset and progression of AIS. SUMMARY OF BACKGROUND DATA: Previous studies have identified several rare variants in FBN1 and FBN2 that...

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Source

Identifiers

PMID: 30044367
DOI: 10.1097/BRS.0000000000002809

Genes

FBN1
FBN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.PMID 30044367Read ↗

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