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Article

Alternative splicing and subfunctionalization generates functional diversity in fungal proteomes.

PLoS genetics - 1 Jan 2013

Marshall Alexandra N, Montealegre Maria Camila, Jiménez-López Claudia, Lorenz Michael C, van Hoof Ambro

Abstract excerpt

Alternative splicing is commonly used by the Metazoa to generate more than one protein from a gene. However, such diversification of the proteome by alternative splicing is much rarer in fungi. We describe here an ancient fungal alternative splicing event in which these two proteins are generated from a single alternatively spliced ancestral SKI7/HBS1 gene retained in many species in both the Ascomycota and...

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Identifiers

PMID: 23516382
DOI: 10.1371/journal.pgen.1003376
PMCID: PMC3597508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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