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Article

Intrinsic Oncogenic Function of Intracellular Connexin26 Protein in Head and Neck Squamous Cell Carcinoma Cells.

International journal of molecular sciences - 23 Jul 2018

Iikawa Nobuko, Yamamoto Yohei, Kawasaki Yohei, Nishijima-Matsunobu Aki, Suzuki Maya, Yamada Takechiyo, Omori Yasufumi

Abstract excerpt

It has long been known that the gap junction is down-regulated in many tumours. One of the downregulation mechanisms is the translocation of connexin, a gap junction protein, from cell membrane into cytoplasm, nucleus, or Golgi apparatus. Interestingly, as tumours progress and reinforce their malignant phenotype, the amount of aberrantly-localised connexin increases in different malignant tumours including...

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Identifiers

PMID: 30041406
DOI: 10.3390/ijms19072134
PMCID: PMC6073371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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