Article
Pedigree Selection and Information Content.
Current protocols in human genetics - 1 Apr 2018
Vardarajan Badri N, Beecham Gary W, Haines Jonathan L
Abstract excerpt
In this article, we discuss strategies for selection of families and family members for genetic studies. We will evaluate strategies to sample large families with multiply affected members, sibships, and nuclear families. In addition, we have added a section to discuss sub-sampling within pedigrees for large sequencing studies, particularly when genome-wide SNP chips are available on all members of a pedigree....
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