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Article

The importance of family-based sampling for biobanks.

Nature - 1 Oct 2024

Davies Neil M, Hemani Gibran, Neiderhiser Jenae M, Martin Hilary C, Mills Melinda C, Visscher Peter M, Yengo Loïc, Young Alexander Strudwick, Keller Matthew C

Abstract excerpt

Biobanks aim to improve our understanding of health and disease by collecting and analysing diverse biological and phenotypic information in large samples. So far, biobanks have largely pursued a population-based sampling strategy, where the individual is the unit of sampling, and familial relatedness occurs sporadically and by chance. This strategy has been remarkably efficient and successful, leading to...

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Identifiers

PMID: 39443775
DOI: 10.1038/s41586-024-07721-5
PMCID: PMC11623399

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