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Article

Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4

20 Jul 2018

Abstract excerpt

BACKGROUND: An increasing number of studies have recently reported that microRNAs packaged in exosomes contribute to multiple biological processes such as cancer progression; however, little is known about their role in the development of radiation-induced bystander effects. METHODS: The exosomes were isolated from the culture medium of BEP2D cells with or without γ-ray irradiation by ultracentrifugation. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30038324
DOI: 10.1038/s41416-018-0192-9

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