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Article

Exosome-Mediated Telomere Instability in Human Breast Epithelial Cancer Cells after X Irradiation

13 Dec 2016

Abstract excerpt

In directly irradiating cells, telomere metabolism is altered and similar effects have been observed in nontargeted cells. Exosomes and their cargo play dominant roles in communicating radiation-induced bystander effects with end points related to DNA damage. Here we report novel evidence that exosomes are also responsible for inducing telomere-related bystander effects. Breast epithelial cancer cells were...

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PMID: 27959588
DOI: 10.1667/rr14201.1

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