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Article

microRNAs in Cancer Cell Response to Ionizing Radiation

10 Nov 2013

Abstract excerpt

SIGNIFICANCE: microRNAs (miRNA) have been characterized as master regulators of the genome. As such, miRNAs are responsible for regulating almost every cellular pathway, including the DNA damage response (DDR) after ionizing radiation (IR). IR is a therapeutic tool that is used for the treatment of several types of cancer, yet the mechanism behind radiation response is not fully understood. RECENT ADVANCES: It...

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PMID: 24206455
DOI: 10.1089/ars.2013.5718

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