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Article

Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo

7 Mar 2007

Abstract excerpt

Radiation therapy is a primary treatment modality for brain tumors, yet it has been linked to the increased incidence of secondary, post-radiation therapy cancers. These cancers are thought to be linked to indirect radiation-induced bystander effect. Bystander effect occurs when irradiated cells communicate damage to nearby, non-irradiated 'bystander' cells, ultimately contributing to genome destabilization in...

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PMID: 17347136
DOI: 10.1093/carcin/bgm053

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