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Article

microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways

19 Jul 2010

Abstract excerpt

The radiation-induced bystander effect (RIBE) is a phenomenon whereby unexposed cells exhibit molecular symptoms of stress exposure when adjacent or nearby cells are traversed by ionizing radiation (IR). Recent data suggest that RIBE may be epigenetically mediated by microRNAs (miRNAs), which are small regulatory molecules that target messenger RNA transcripts for translational inhibition. Here, we analyzed...

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PMID: 20643754
DOI: 10.1093/carcin/bgq119

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