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Article

MGMT gene promoter methylation and its correlation with clinicopathological parameters in glioblastomas.

Neurology India - 1 Jan 2000

Arora Iteeka, Gurav Mamta, Rumde Rachna, Dhanavade Sandeep, Kadam Vinayak, Kurani Hetakshi, Shetty Omshree, Goda Jayant Sastri, Shetty Prakash, Moiyadi Aliasgar, Gupta Tejpal, Jalali Rakesh, Epari Sridhar

Abstract excerpt

BACKGROUND: MGMT (O6-methyl guanine DNA methyl transferase) promoter hypermethylation is a prognostic and predictive biomarker for glioblastomas (GBM). AIMS: To evaluate the frequency of MGMT methylation status in a single institute series of 134 GBMs and correlate it with clinical (age, sex, location, survival) and other molecular parameters [such as p53 expression, alpha thalassemia/mental retardation syndrome...

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Share to Brain Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA Repair Enzymes

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Share to Isocitrate Dehydrogenase

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Source

Identifiers

PMID: 30038102
DOI: 10.4103/0028-3886.236974

Genes

MGMT
ATRX
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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