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MGMT Promoter Methylation: Prognostication beyond Treatment Response

14 Jun 2023

Abstract excerpt

MGMT promoter methylation is related to the increased sensitivity of tumour tissue to chemotherapy with temozolomide (TMZ) and thus to improved patient survival. However, it is unclear how the extent of MGMT promoter methylation affects outcomes. In our study, a single-centre retrospective study, we explore the impact of MGMT promoter methylation in patients with glioblastoma who were operated upon with 5-ALA....

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PMID: 37373988
DOI: 10.3390/jpm13060999

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