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Article

Inactivation of autophagy leads to changes in sebaceous gland morphology and function.

Experimental dermatology - 1 Oct 2018

Rossiter Heidemarie, Stübiger Gerald, Gröger Marion, König Ulrich, Gruber Florian, Sukseree Supawadee, Mlitz Veronika, Buchberger Maria, Oskolkova Olga, Bochkov Valery, Eckhart Leopold, Tschachler Erwin

Abstract excerpt

We have reported recently that inactivation of the essential autophagy-related gene 7 (Atg7) in keratinocytes has little or no impact on morphology and function of the epidermal barrier in experimental animals. When these mice aged, mutant males, (Atg7 ΔKC), developed an oily coat. As the keratin 14 promoter driven cre/LoxP system inactivates floxed Atg7 in all keratin 14 (K14) expressing cells, including...

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PMID: 30033522
DOI: 10.1111/exd.13752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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