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Article

Autophagy deficient melanocytes display a senescence associated secretory phenotype that includes oxidized lipid mediators.

The international journal of biochemistry & cell biology - 1 Dec 2016

Ni Chunya, Narzt Marie-Sophie, Nagelreiter Ionela-Mariana, Zhang Cheng Feng, Larue Lionel, Rossiter Heidemarie, Grillari Johannes, Tschachler Erwin, Gruber Florian

Abstract excerpt

Autophagy is a recycling program which allows cells to adapt to metabolic needs and to stress. Defects in autophagy can affect metabolism, aging, proteostasis and inflammation. Autophagy pathway genes, including autophagy related 7 (Atg7), have been associated with the regulation of skin pigmentation, and autophagy defects disturb the biogenesis and transport of melanosomes in melanocytes as well as transfer and...

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Identifiers

PMID: 27732890
DOI: 10.1016/j.biocel.2016.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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