Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagy drives epidermal deterioration in a Drosophila model of tissue aging.

Aging - 1 Apr 2013

Scherfer Christoph, Han Violet C, Wang Yan, Anderson Aimee E, Galko Michael J

Abstract excerpt

Organismal lifespan has been the primary readout in aging research. However, how longevity genes control tissue-specific aging remains an open question. To examine the crosstalk between longevity programs and specific tissues during aging, biomarkers of organ-specific aging are urgently needed. Since the earliest signs of aging occur in the skin, we sought to examine skin aging in a genetically tractable model....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Autophagy
Share to Biomarkers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Gene Expression Regulation

Share to Mutation

Share to Vertebrates

Source

Open in PubMed Open full text

Identifiers

PMID: 23599123
DOI: 10.18632/aging.100549
PMCID: PMC3651520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy drives epidermal deterioration in a Drosophila model of tissue aging.PMID 23599123Read ↗

Autophagic Control of Skin AgingSemantic proximity Read ↗

Autophagy in Human Skin Fibroblasts: Impact of AgeSemantic proximity Read ↗

Epidermal keratinocytes form a functional skin barrier in the absence of Atg7 dependent autophagySemantic proximity Read ↗

Hallmarks of Skin Aging: UpdateSemantic proximity Read ↗

Autophagy Declines with Premature Skin Aging resulting in Dynamic Alterations in Skin Pigmentation and Epidermal DifferentiationSemantic proximity Read ↗

Faces of cellular senescence in skin agingSemantic proximity Read ↗

On the Fly: Recent Progress on Autophagy and Aging in DrosophilaSemantic proximity Read ↗

The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseasesSemantic proximity Read ↗

Skin senescence: mechanisms and impact on whole-body aging.Semantic proximity Read ↗

More Than Skin Deep: Autophagy Is Vital for Skin Barrier FunctionSemantic proximity Read ↗

Autophagy: Guardian of Skin BarrierSemantic proximity Read ↗

Cell death induced autophagy contributes to terminal differentiation of skin and skin appendagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.