Article
Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring.
The Journal of antimicrobial chemotherapy - 1 Nov 2018
Villa Giovanni, Phillips Richard O, Smith Colette, Stockdale Alexander J, Ruggiero Alessandra, Beloukas Apostolos, Appiah Lambert T, Chadwick David, Sarfo Fred S, Geretti Anna Maria
Abstract excerpt
Objectives: The resistance profiles of patients receiving long-term ART in sub-Saharan Africa have been poorly described. This study obtained a sensitive assessment of the resistance patterns associated with long-term tenofovir-based ART in a programmatic setting where virological monitoring is yet to become part of routine care. Methods: We studied subjects who, after a median of 4.2 years of ART, replaced...
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