Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Cell Line-based Immunohistochemical p53 Expression Pattern Control Panel.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Sept 2019

Hussain Imran, Howard Robin S, Syed Viqar, Allgäuer Michael, Gong Heping, Xing Deyin, Andersen John D

Abstract excerpt

TP53 gene mutations are known to manifest in distinct p53 immunohistochemical staining patterns; overexpression, wild-type, and null. These stratified staining patterns are routinely utilized in subtyping ovarian cancer subtypes. Three ovarian cancer cell lines were used in the construction of an immunohistochemical p53 expression pattern control panel that highlight respective TP53 mutation status. The cell line...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Immunohistochemistry

Share to Mutation

Share to Ovarian Neoplasms

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 30028355
DOI: 10.1097/PGP.0000000000000537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Cell Line-based Immunohistochemical p53 Expression Pattern Control Panel.PMID 30028355Read ↗

Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: an immunohistochemical and nucleotide sequencing analysis.Semantic proximity Read ↗

Correlation analysis of TP53 missense mutations and p53 protein expression patterns in endometrial carcinoma.Semantic proximity Read ↗

Molecular Alterations of TP53 are a Defining Feature of Ovarian High-Grade Serous Carcinoma: A Rereview of Cases Lacking TP53 Mutations in The Cancer Genome Atlas Ovarian Study.Semantic proximity Read ↗

Refined criteria for p53 expression in ovarian mucinous tumours are highly concordant with TP53 mutation status, but p53 expression/TP53 status lack prognostic significance.Semantic proximity Read ↗

p53 null phenotype is a "positive result" in urothelial carcinoma in situ.Semantic proximity Read ↗

The pattern-based interpretation of p53 immunohistochemical expression as a surrogate marker for TP53 mutations in colorectal cancerSemantic proximity Read ↗

p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations.Semantic proximity Read ↗

IHC p53 Performance in NordiQC: Recalibration of IHC Assays is Needed.Semantic proximity Read ↗

Performance of the pattern-based interpretation of p53 immunohistochemistry as a surrogate for TP53 mutations in vulvar squamous cell carcinoma.Semantic proximity Read ↗

p53 Immunohistochemical Staining and TP53 Gene Mutations in Endometrial Cancer: Does Null Pattern Correlate With Prognosis?Semantic proximity Read ↗

Analytical Validation of AmpliChip p53 Research Test for Archival Human Ovarian FFPE Sections.Semantic proximity Read ↗

Optimized p53 immunohistochemistry is an accurate predictor of <i>TP53</i> mutation in ovarian carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.