Article
Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood.
Pediatric blood & cancer - 1 Sept 2018
Hankins Jane S, Estepp Jeremie H, Hodges Jason R, Villavicencio Martha A, Robison Leslie L, Weiss Mitchell J, Kang Guolian, Schreiber Jane E, Porter Jerlym S, Kaste Sue C, Saving Kay L, Bryant Paulette C, Deyo Jeffrey E, Nottage Kerri A, King Allison A, Brandow Amanda M, Lebensburger Jeffrey D, Adesina Oyebimpe, Chou Stella T, Zemel Babette S, Smeltzer Matthew P, Wang Winfred C, Gurney James G
Abstract excerpt
BACKGROUND: Previous natural history studies have advanced the understanding of sickle cell disease (SCD), but generally have not included sufficient lifespan data or investigation of the role of genetics in clinical outcomes, and have often occurred before the widespread use of disease-modifying therapies, such as hydroxyurea and chronic erythrocyte transfusions. To further advance knowledge of SCD, St. Jude...
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