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Article

MRI Phenotype of RELA-fused Pediatric Supratentorial Ependymoma.

Clinical neuroradiology - 1 Dec 2019

Nowak Johannes, Jünger Stephanie Theresa, Huflage Henner, Seidel Carolin, Hohm Annika, Vandergrift Lindsey A, von Hoff Katja, Rutkowski Stefan, Pietsch Torsten, Warmuth-Metz Monika

Abstract excerpt

PURPOSE: Epigenetic profiling has recently identified clinically and molecularly distinct subgroups of ependymoma. The 2016 World Health Organization (WHO) classification recognized supratentorial ependymomas (ST-EPN) with REL-associated protein/p65 (RELA) fusion as a clinicopathological entity. These tumors represent 70% of pediatric ST-EPN characterized by recurrent C11orf95-RELA fusion transcripts, which lead...

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Source

Identifiers

PMID: 30027327
DOI: 10.1007/s00062-018-0704-2

Genes

RELA
REL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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