Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions.

doi:10.1186/s40478-021-01238-y

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Article

Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions.

Acta neuropathologica communications - 13 Aug 2021

Tauziède-Espariat Arnault, Siegfried Aurore, Nicaise Yvan, Kergrohen Thomas, Sievers Philipp, Vasiljevic Alexandre, Roux Alexandre, Dezamis Edouard, Benevello Chiara, Machet Marie-Christine, Michalak Sophie, Puiseux Chloe, Llamas-Gutierrez Francisco, Leblond Pierre, Bourdeaut Franck, Grill Jacques, Dufour Christelle, Guerrini-Rousseau Léa, Abbou Samuel, Dangouloff-Ros Volodia, Boddaert Nathalie, Saffroy Raphaël, Hasty Lauren, Wahler Ellen, Pagès Mélanie, Andreiuolo Felipe, Lechapt Emmanuèle, Chrétien Fabrice, Blauwblomme Thomas, Beccaria Kévin, Pallud Johan, Puget Stéphanie, Uro-Coste Emmanuelle, Varlet Pascale

Abstract excerpt

The cIMPACT-NOW Update 7 has replaced the WHO nosology of "ependymoma, RELA fusion positive" by "Supratentorial-ependymoma, C11orf95-fusion positive". This modification reinforces the idea that supratentorial-ependymomas exhibiting fusion that implicates the C11orf95 (now called ZFTA) gene with or without the RELA gene, represent the same histomolecular entity. A hot off the press molecular study has identified...

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PMID: 34389065
DOI: 10.1186/s40478-021-01238-y
PMCID: PMC8362233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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