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Article

Genistein induces macrophage polarization and systemic cytokine to ameliorate experimental colitis.

PloS one - 1 Jan 2018

Abron Jessicca D, Singh Narendra P, Price Robert L, Nagarkatti Mitzi, Nagarkatti Prakash S, Singh Udai P

Abstract excerpt

Mucosal changes in Crohn's disease (CD) and ulcerative colitis (UC), two major forms of inflammatory bowel disease (IBD), are characterized by a prominent infiltration of inflammatory cells including lymphocytes, macrophages, T cells and neutrophils. The precise etiology of IBD is unknown but it involves a complex interplay of factors associated with the immune system, environment, host genotype and enteric...

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Source

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Identifiers

PMID: 30024891
DOI: 10.1371/journal.pone.0199631
PMCID: PMC6053137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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