Article
Toward a comprehensive prognostic scoring system in chronic lymphocytic leukemia based on a combination of genetic parameters.
Genes, chromosomes & cancer - 1 Sept 2010
Haferlach Claudia, Dicker Frank, Weiss Tamara, Schnittger Susanne, Beck Christian, Grote-Metke Albert, Oruzio Daniel, Kern Wolfgang, Haferlach Torsten
Abstract excerpt
Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with a variable clinical course. The aim of this study was to evaluate whether a combination of genetic parameters can improve prediction of outcome irrespective of clinical stage. The prognostic impact of chromosome banding analysis (CBA) in addition to FISH and IgVH mutation status was evaluated. In total, 482 patients were analyzed, but evaluation...
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