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Article

Soluble (pro)renin receptor as a potential therapy for diabetes insipidus.

American journal of physiology. Renal physiology - 1 Nov 2018

Yang Kevin T, Yang Tianxin, Symons J David

Abstract excerpt

The antidiuretic hormone vasopressin (VP) is produced by the hypothalamus and is stored and secreted from the posterior pituitary. VP acts via VP type 2 receptors (V2Rs) on the basolateral membrane of principal cells of the collecting duct (CD) to regulate fluid permeability. The VP-evoked endocrine pathway is essential in determining urine concentrating capability. For example, a defect in any component of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30019932
DOI: 10.1152/ajprenal.00266.2018
PMCID: PMC6293289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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