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Article

A Xenobiotic Detoxification Pathway through Transcriptional Regulation in Filamentous Fungi.

mBio - 17 Jul 2018

Sang Hyunkyu, Hulvey Jonathan P, Green Robert, Xu Hao, Im Jeongdae, Chang Taehyun, Jung Geunhwa

Abstract excerpt

Fungi are known to utilize transcriptional regulation of genes that encode efflux transporters to detoxify xenobiotics; however, to date it is unknown how fungi transcriptionally regulate and coordinate different phases of detoxification system (phase I, modification; phase II, conjugation; and phase III, secretion). Here we present evidence of an evolutionary convergence between the fungal and mammalian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30018104
DOI: 10.1128/mBio.00457-18
PMCID: PMC6050962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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