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Importance of Clinical Isolates in Cryptococcus neoformans Research

16 Mar 2023

Abstract excerpt

The human pathogenic fungus Cryptococcus neoformans is a global health concern. Previous research in the field has focused on studies using reference strains to identify virulence factors, generate mutant libraries, define genomic structures, and perform functional studies. In this review, we discuss the benefits and drawbacks of using reference strains to study C. neoformans, describe how the study of clinical...

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PMID: 36983532
DOI: 10.3390/jof9030364

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