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Article

ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.

The American journal of surgical pathology - 1 Oct 2018

Mohammad Nissreen, Haimes Josh D, Mishkin Skyler, Kudlow Brian A, Leong May Ying, Chew Sung Hock, Koay Eleanor, Whitehouse Ann, Cope Nichola, Ali Rola H, Köbel Martin, Stewart Colin J R, McCluggage W Glenn, Lee Cheng-Han

Abstract excerpt

Inflammatory myofibroblastic tumor (IMT) is a myofibroblastic/fibroblastic neoplasm of intermediate malignant potential. It is frequently characterized by genetic fusion of ALK with a variety of partner genes, which results in the activated ALK signaling pathway that can be targeted with kinase inhibitors. IMTs can occur in the gynecologic tract, with the uterus (corpus and cervix) being the most frequent site....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30015720
DOI: 10.1097/PAS.0000000000001120

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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