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Prognostic impact of ASXL1 mutations in patients with myelodysplastic syndromes and multilineage dysplasia with or without ring sideroblasts.

Leukemia research - 1 Aug 2018

Mangaonkar Abhishek A, Gangat Naseema, Al-Kali Aref, Elliott Michelle A, Begna Kebede H, Hanson Curtis A, Ketterling Rhett P, Wolanskyj-Spinner Alexandra P, Hogan William J, Litzow Mark R, Patnaik Mrinal M

Abstract excerpt

INTRODUCTION: The 2016 World Health Organization (WHO) classification of myeloid neoplasms reclassified patients with myelodysplastic syndromes (MDS) with multilineage dysplasia (MLD) based on the presence or absence of ring sideroblasts (RS). We performed this study to validate this change in the context of relevant gene mutations. METHODS: WHO-defined MDS and MLD were identified with detailed clinical,...

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PMID: 30015104
DOI: 10.1016/j.leukres.2018.07.010

Genes

ASXL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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