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Article

Genetic, Biochemical, and Molecular Characterization of Methanosarcina barkeri Mutants Lacking Three Distinct Classes of Hydrogenase.

Journal of bacteriology - 15 Oct 2018

Mand Thomas D, Kulkarni Gargi, Metcalf William W

Abstract excerpt

The methanogenic archaeon Methanosarcina barkeri encodes three distinct types of hydrogenase, whose functions vary depending on the growth substrate. These include the F420-dependent (Frh), methanophenazine-dependent (Vht), and ferredoxin-dependent (Ech) hydrogenases. To investigate their physiological roles, we characterized a series of mutants lacking each hydrogenase in various combinations. Mutants lacking...

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Identifiers

PMID: 30012731
DOI: 10.1128/JB.00342-18
PMCID: PMC6153667

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Source receipt: pubmed, retrieved 7 Sept 2026.

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