Article
Mutagenesis of the C1 oxidation pathway in Methanosarcina barkeri: new insights into the Mtr/Mer bypass pathway.
Journal of bacteriology - 1 Mar 2008
Welander Paula V, Metcalf William W
Abstract excerpt
A series of Methanosarcina barkeri mutants lacking the genes encoding the enzymes involved in the C1 oxidation/reduction pathway were constructed. Mutants lacking the methyl-tetrahydromethanopterin (H4MPT):coenzyme M (CoM) methyltransferase-encoding operon (delta mtr), the methylene-H4MPT reductase-encoding gene (delta mer), the methylene-H4MPT dehydrogenase-encoding gene (delta mtd), and the...
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