Article
A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer's disease.
GigaScience - 1 Jul 2018
Zhang Hongjiu, Zhu Fan, Dodge Hiroko H, Higgins Gerald A, Omenn Gilbert S, Guan Yuanfang
Abstract excerpt
Motivation: Heterogeneous diseases such as Alzheimer's disease (AD) manifest a variety of phenotypes among populations. Early diagnosis and effective treatment offer cost benefits. Many studies on biochemical and imaging markers have shown potential promise in improving diagnosis, yet establishing quantitative diagnostic criteria for ancillary tests remains challenging. Results: We have developed a...
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