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Article

mTOR'ing across the Cortex by Chopping the Cilia.

Neuron - 11 Jul 2018

Di Nardo Alessia, Sahin Mustafa

Abstract excerpt

Somatic mutation of the MTOR gene is a genetic etiology of focal malformations of cortical development. In this issue of Neuron, Park et al. (2018) identify defective autophagy-dependent ciliogenesis/Wnt signaling as an underlying mechanism affecting neuronal migration and cortical lamination.

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Source

Identifiers

PMID: 30001510
DOI: 10.1016/j.neuron.2018.06.042

Genes

MTOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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mTOR'ing across the Cortex by Chopping the Cilia.PMID 30001510Read ↗

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mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortexSemantic proximity Read ↗

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mTOR: A pathogenic signaling pathway in developmental brain malformations.Semantic proximity Read ↗

Caveat mTOR: aberrant signaling disrupts corticogenesis.Semantic proximity Read ↗

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