Article
Comprehensive molecular profiling of the B7 family in gastrointestinal cancer.
Cell proliferation - 1 Oct 2018
Zhao Qijie, Hu Fuyan, Xiao Zhangang, Li Mingxing, Wu Xu, Zhao Yueshui, Wu Yuanlin, Yin Jianhua, Lin Ling, Zhang Hanyu, Zhang Lingling, Cho Chi Hin, Shen Jing
Abstract excerpt
OBJECTIVES: B7 family has been identified as co-stimulatory or co-inhibitory molecules on T-cell response and plays an important role in tumour mortality and malignancy. In this study, the expression pattern of B7 family in gastrointestinal (GI) cancer was examined. Its upstream regulating mechanism, downstream targets and association with clinical parameters were also studied. MATERIALS AND METHODS: The...
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