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Article

A human population-based organotypic in vitro model for cardiotoxicity screening.

ALTEX - 1 Jan 2018

Grimm Fabian A, Blanchette Alexander, House John S, Ferguson Kyle, Hsieh Nan-Hung, Dalaijamts Chimeddulam, Wright Alec A, Anson Blake, Wright Fred A, Chiu Weihsueh A, Rusyn Ivan

Abstract excerpt

Assessing inter-individual variability in responses to xenobiotics remains a substantial challenge, both in drug development with respect to pharmaceuticals and in public health with respect to environmental chemicals. Although approaches exist to characterize pharmacokinetic variability, there are no methods to routinely address pharmacodynamic variability. In this study, we aimed to demonstrate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29999168
DOI: 10.14573/altex.1805301
PMCID: PMC6231908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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