Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of HPV-induced DNA Damage Repair Factors Correlates With CIN Progression.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2019

Spriggs Chelsey C, Blanco Luis Z, Maniar Kruti P, Laimins Laimonis A

Abstract excerpt

Human papillomaviruses (HPVs) are DNA viruses with epithelial tropism. High-risk types of HPV are the causative agents of the majority of cervical cancers and are responsible for a number of other anogenital as well as oropharyngeal cancers. The life cycle of HPV is closely linked to the differentiation state of its host cell and is dependent on the activation of specific pathways of the DNA damage response....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervix Uteri
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Papillomaviridae

Share to Papillomavirus Infections

Share to Uterine Cervical Dysplasia

Share to Uterine Cervical Neoplasms

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 29995652
DOI: 10.1097/PGP.0000000000000477
PMCID: PMC6295252

Genes

BRCA1
FANCD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of HPV-induced DNA Damage Repair Factors Correlates With CIN Progression.PMID 29995652Read ↗

FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral ReplicationSemantic proximity Read ↗

Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral ReplicationSemantic proximity Read ↗

Different DNA damage and cell cycle checkpoint control in low‐ and high‐risk human papillomavirus infections of the vulvaSemantic proximity Read ↗

Genomic Instability and DNA Damage Repair Pathways Induced by Human Papillomaviruses.Semantic proximity Read ↗

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication CentersSemantic proximity Read ↗

Human Papillomaviruses Activate and Recruit SMC1 Cohesin Proteins for the Differentiation-Dependent Life Cycle through Association with CTCF InsulatorsSemantic proximity Read ↗

High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2Semantic proximity Read ↗

High-Risk Human Papillomavirus Oncogenes Disrupt the Fanconi Anemia DNA repair Pathway by Impairing Localization and Deubiquitination of FancD2Semantic proximity Read ↗

STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus ReplicationSemantic proximity Read ↗

Virus-host interaction: investigating novel transcription factors involved in coupling HPV life cycle and epithelial differentiationSemantic proximity Read ↗

The Fanconi Anemia Pathway Limits Human Papillomavirus ReplicationSemantic proximity Read ↗

Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.