Article
Novel minor HLA DR associated antigens in type 1 diabetes.
Clinical immunology (Orlando, Fla.) - 1 Sept 2018
Müller Denise, Telieps Tanja, Eugster Anne, Weinzierl Christina, Jolink Manja, Ziegler Anette-Gabriele, Bonifacio Ezio
Abstract excerpt
Type 1 diabetes is an autoimmune disease leading to insulin deficiency. Autoantibodies to beta cell proteins are already present in the asymptomatic phase of type 1 diabetes. Recent findings have suggested a number of additional minor autoantigens in patients with type 1 diabetes. We have established luciferase immunoprecipitation systems (LIPS) for anti-MTIF3, anti-PPIL2, anti-NUP50 and anti-MLH1 and analyzed...
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