Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Genes Variants in RANKL/RANK/OPG Signaling Pathway with the Development of Osteonecrosis of the Femoral Head in Chinese Population.

International journal of medical sciences - 1 Jan 2017

Song Yang, Du Zhen-Wu, Yang Qi-Wei, Ren Ming, Wang Qing-Yu, Wang Ao, Chen Gao-Yang, Zhao Hai-Yue, Yu Tao, Zhang Gui-Zhen

Abstract excerpt

The RANKL/RANK/OPG pathway plays an important role in regulating bone remodeling and bone turnover. However, the association of the genes variants with the risk of ONFH has rarely been reported. Here, we analyzed the correlation of the 10 SNPs polymorphisms of RANKL, RANK, OPG, TRAF6, and NFATC1 genes with the risk and development of ONFH in 200 ONFH patients and 177 health controls of Chinese population with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Femur Head Necrosis
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NFATC Transcription Factors

Share to Osteonecrosis

Share to Osteoprotegerin

Share to RANK Ligand

Share to Receptor Activator of Nuclear Factor-kappa B

Share to Tumor Necrosis Factor Receptor-Associated Peptides and Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28824302
DOI: 10.7150/ijms.19124
PMCID: PMC5562121

Genes

NFATC1
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Genes Variants in RANKL/RANK/OPG Signaling Pathway with the Development of Osteonecrosis of the Femoral Head in Chinese Population.PMID 28824302Read ↗

Association of Variant Interactions in RANK , RANKL , OPG , TRAF6 , and NFATC1 Genes with the Development of Osteonecrosis of the Femoral HeadSemantic proximity Read ↗

Association of gene variants of transcription factors PPARγ, RUNX2, Osterix genes and COL2A1, IGFBP3 genes with the development of osteonecrosis of the femoral head in Chinese population.Semantic proximity Read ↗

OPG and RANKL polymorphisms are associated with alcohol-induced osteonecrosis of the femoral head in the north area of China population in men.Semantic proximity Read ↗

17 variants interaction of Wnt/β-catenin pathway associated with development of osteonecrosis of femoral head in Chinese Han population.Semantic proximity Read ↗

DNA Methylation in OPG/RANK/RANKL Pathway is Associated with Steroid-induced Osteonecrosis of the Femoral HeadSemantic proximity Read ↗

Association between genetic polymorphisms of MMP8 and the risk of steroid-induced osteonecrosis of the femoral head in the population of northern China.Semantic proximity Read ↗

FTO rs62033406 A>G associated with the risk of osteonecrosis of the femoral head among the Chinese Han population.Semantic proximity Read ↗

DNA methylation in the OPG/RANK/RANKL pathway is associated with steroid-induced osteonecrosis of the femoral headSemantic proximity Read ↗

OPG / RANKL / RANK Gene Methylation Among Alcohol-induced Femoral Head Necrosis in Northern Chinese MenSemantic proximity Read ↗

Association between LINC-PINT and LINC00599 gene polymorphism and the risk of steroid-induced osteonecrosis of the femoral head in the population of northern China.Semantic proximity Read ↗

Osteoprotegerin polymorphisms are associated with alcohol-induced osteonecrosis of femoral head in Chinese Han population from Henan province.Semantic proximity Read ↗

Integrative analyses of genes related to femoral head osteonecrosis: an umbrella review of systematic reviews and meta-analyses of observational studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.