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Article

The association of AKNA gene polymorphisms with knee osteoarthritis suggests the relevance of this immune response regulator in the disease genetic susceptibility.

Molecular biology reports - 1 Apr 2018

Martínez-Nava Gabriela Angélica, Fernández-Torres Javier, Martínez-Flores Karina, Zamudio-Cuevas Yessica, Clavijo-Cornejo Denise, Espinosa-Morales Rolando, Lozada Carlos A, Gutierrez Marwin, Granados Julio, Pineda Carlos, Madrid-Marina Vicente, López-Reyes Alberto

Abstract excerpt

Recent studies have identified AKNA as a potential susceptibility gene for several inflammatory diseases. Here, we aimed to assess the potential association of AKNA polymorphisms with knee osteoarthritis (KOA) susceptibility in a Mexican population, following STREGA recommendations. From a DNA bank of 181 KOA patients and 140 healthy controls, two AKNA SNPs were genotyped using TaqMan probes. The association...

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PMID: 29368274
DOI: 10.1007/s11033-018-4148-1

Genes

AKNA

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