Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discovery of a dual protease mechanism that promotes DNA damage checkpoint recovery.

PLoS genetics - 1 Jul 2018

Burby Peter E, Simmons Zackary W, Schroeder Jeremy W, Simmons Lyle A

Abstract excerpt

The DNA damage response is a signaling pathway found throughout biology. In many bacteria the DNA damage checkpoint is enforced by inducing expression of a small, membrane bound inhibitor that delays cell division providing time to repair damaged chromosomes. How cells promote checkpoint recovery after sensing successful repair is unknown. By using a high-throughput, forward genetic screen, we identified two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacillus subtilis
Share to Cell Cycle Checkpoints
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Damage

Share to DNA Repair

Share to DNA Transposable Elements

Share to Endopeptidases

Share to Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 29979679
DOI: 10.1371/journal.pgen.1007512
PMCID: PMC6051672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discovery of a dual protease mechanism that promotes DNA damage checkpoint recovery.PMID 29979679Read ↗

An essential protease involved in bacterial cell-cycle control.Semantic proximity Read ↗

YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.Semantic proximity Read ↗

A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW.Semantic proximity Read ↗

The CtrA response regulator essential for Caulobacter crescentus cell-cycle progression requires a bipartite degradation signal for temporally controlled proteolysis.Semantic proximity Read ↗

Cryptic adaptor protein interactions regulate DNA replication initiationSemantic proximity Read ↗

A WYL transcriptional regulator activates the DNA damage response pathway in Acinetobacter species.Semantic proximity Read ↗

Positive and negative control of helicase recruitment at a bacterial chromosome originSemantic proximity Read ↗

A nutrient-dependent division antagonist is regulated post-translationally by the Clp proteases in Bacillus subtilis.Semantic proximity Read ↗

Deciphering proteolysis pathways for the error-prone DNA polymerase in cyanobacteria.Semantic proximity Read ↗

A signal transduction protein cues proteolytic events critical to Caulobacter cell cycle progression.Semantic proximity Read ↗

DrpB (YedR) Is a Nonessential Cell Division Protein in Escherichia coli.Semantic proximity Read ↗

Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.